Meropenem+Sulbactam is used in the treatment of severe bacterial infections.How Meropenem + Sulbactam worksMeropenem + Sulbactam is a combination of two medicines: Meropenem and Sulbactam. Meropenem is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Sulbactam is a beta-lactamase inhibitor which blocks the action of enzymes produced by bacteria to inactivate Meropenem . Addition of Sulbactam reduces resistance and enhances the activity of Meropenem against bacteria.