Desloratadine belongs to a group of medications known as antihistamines, specifically the class known as H1- receptors antagonists. The medication is used to relief the symptoms of seasonal and year round allergies. It is also used to relief the symptoms of allergic skin conditions. In skin allergy & rhinitis condition:Potent H1, receptor antagonistMast cell stabilizer, prevents histamine releaseApproved for use in pilotsCan be prescribed in renal & cardiac patients