Drotaverine Hydrochloride Tablets IP (typically 40mg) are a potent antispasmodic medication used to relieve smooth muscle spasms and cramps in the gastrointestinal tract, uterus, and biliary system. It is widely used to treat pain from conditions like menstrual cramps, gallbladder stones, and kidney stones. CARE Hospitals +3Description and Mechanism of Action:
Classification: It is a benzylisoquinoline derivative, a selective phosphodiesterase-4 (PDE4) inhibitor.
Mechanism: It works as a smooth muscle relaxant, reducing muscle contractions (spasms) and relieving visceral pain. It is more potent than papaverine.
Common Use: Treats intestinal colic, irritable bowel syndrome (IBS), gastritis, enteritis, and painful menstruation (dysmenorrhea). nestoronline +4
Dosage and Administration:
Adults: Usually 1-2 tablets (40 mg each) taken three times daily.
Administration: It can be taken with or without food, but taking it with food may reduce the chance of an upset stomach.
Important: Consult a doctor for appropriate dosage based on the condition. CARE Hospitals +2
Side Effects:Common side effects are generally mild and may include:
Nausea and vomiting
Dry mouth
Dizziness or vertigo
Headache or insomnia
Blood pressure drop (hypotension) PharmEasy +3
Precautions and Warnings:
Liver/Heart/Kidney Disease: Use with caution and only under medical supervision if you have severe impairment.
Pregnancy/Breastfeeding: Consult a doctor before use; it is often not recommended.
Driving: Because it can cause dizziness, avoid driving or operating machinery if affected.
Alcohol: Avoid alcohol as it can increase dizziness