Infliximab Powder For Injection In Pune

Infimab Injection is used for the treatment of various inflammatory conditions of the joints rheumatoid arthritis psoriatic arthritis ankylosing spondylitis skin psoriasis and bowel ulcerative colitis Crohn s disease It reduces inflammation in these conditions by blocking TNF alpha

Product Name: Reliance Inflixirel (Infliximab) Powder for Infusion Brand Name: Inflixirel Composition: Infliximab Strengths Available: 100 mg per vial Packaging Type: Glass Vial Packaging Size: 1 Vial per Pack Prescription Required: Yes Usage/Application: Hospital, Clinical Form: Lyophilized Powder for Intravenous Infusion Country of Origin: India Product Description: Inflixirel is a biosimilar of Infliximab, developed by Reliance Life Sciences. It is a recombinant chimeric human-murine IgG1 monoclonal antibody that binds to both soluble and transmembrane forms of human tumor necrosis factor-alpha (TNF-) and inhibits its functional activity. By neutralizing TNF-, Inflixirel helps reduce inflammation and modulate the immune system in various autoimmune diseases. Key Features: Manufactured by Reliance Life Sciences Available in 100 mg strength Comes as a lyophilized powder for reconstitution Suitable for intravenous administration under medical supervision Packaged in sterile glass vials Manufactured in GMP-compliant facilities Indications: Rheumatoid Arthritis Crohns Disease Ulcerative Colitis Ankylosing Spondylitis Psoriatic Arthritis Plaque Psoriasis Dosage and Administration: Rheumatoid Arthritis: Induction: 3 mg/kg body weight at 0, 2, and 6 weeks Maintenance: 3 mg/kg every 8 weeks Crohns Disease: Induction: 5 mg/kg body weight at 0, 2, and 6 weeks Maintenance: 5 mg/kg every 8 weeks Ulcerative Colitis: Induction: 5 mg/kg body weight at 0, 2, and 6 weeks Maintenance: 5 mg/kg every 8 weeks Ankylosing Spondylitis: Induction: 5 mg/kg body weight at 0, 2, and 6 weeks Maintenance: 5 mg/kg every 8 weeks Psoriatic Arthritis: Induction: 5 mg/kg body weight at 0, 2, and 6 weeks Maintenance: 5 mg/kg every 8 weeks Plaque Psoriasis: Induction: 5 mg/kg body weight at 0, 2, and 6 weeks Maintenance: 5 mg/kg every 8 weeks Reconstitution and Administration: Reconstitute the lyophilized powder with 10 mL of sterile water for injection. Gently swirl the vial to dissolve; do not shake. The reconstituted solution should be clear to slightly opalescent and colorless to pale yellow. Dilute the reconstituted solution with 0.9% Sodium Chloride Injection to a final volume of 250 mL. Administer by intravenous infusion over a period of at least 2 hours. Storage: Store the lyophilized powder at 2C to 8C. Do not freeze. Protect from light. After reconstitution, the solution should be used immediately or stored at 2C to 8C for up to 24 hours.